The replay between the two League One rivals takes place on Wednesday 20th November, the outcome of which will determine the kick-off time.
Should Wycombe progress the match will kick-off at 12.15pm at Adams Park. Should Tranmere be victorious the tie will take place at Prenton Park with the slightly later kick-off time of 3pm.
The match is one of four second round ties that has been selected by broadcasting giants BT Sport and the BBC.
The club is in the process of making preliminary arrangements for travel to both potential locations for supporters wishing to attend the historic match. Those planning on travelling are advised to register interest via the link below.